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3v6y
From Proteopedia
(Difference between revisions)
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==crystal structure of FBF-2 in complex with a mutant gld-1 FBEa13 RNA== | ==crystal structure of FBF-2 in complex with a mutant gld-1 FBEa13 RNA== | ||
| - | <StructureSection load='3v6y' size='340' side='right' caption='[[3v6y]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='3v6y' size='340' side='right'caption='[[3v6y]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3v6y]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3v6y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V6Y FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v71|3v71]], [[3v74|3v74]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3v71|3v71]], [[3v74|3v74]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fbf-2, F21H12.5 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fbf-2, F21H12.5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v6y OCA], [https://pdbe.org/3v6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v6y RCSB], [https://www.ebi.ac.uk/pdbsum/3v6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v6y ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/FBF2_CAEEL FBF2_CAEEL]] Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression possibly by directly binding to two sites within the gld-3 isoform B 3'-UTR.<ref>PMID:9393998</ref> <ref>PMID:15454534</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Caeel]] | [[Category: Caeel]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Hall, T M.T]] | [[Category: Hall, T M.T]] | ||
[[Category: Holley, C H]] | [[Category: Holley, C H]] | ||
Current revision
crystal structure of FBF-2 in complex with a mutant gld-1 FBEa13 RNA
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