3m9q

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Current revision (08:50, 6 September 2023) (edit) (undo)
 
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==Drosophila MSL3 chromodomain==
==Drosophila MSL3 chromodomain==
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<StructureSection load='3m9q' size='340' side='right' caption='[[3m9q]], [[Resolution|resolution]] 1.29&Aring;' scene=''>
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<StructureSection load='3m9q' size='340' side='right'caption='[[3m9q]], [[Resolution|resolution]] 1.29&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3m9q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M9Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3m9q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M9Q FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3m9p|3m9p]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.29&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">msl-3, CG8631 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m9q OCA], [https://pdbe.org/3m9q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m9q RCSB], [https://www.ebi.ac.uk/pdbsum/3m9q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m9q ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m9q OCA], [http://pdbe.org/3m9q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m9q RCSB], [http://www.ebi.ac.uk/pdbsum/3m9q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m9q ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MSL3_DROME MSL3_DROME]] The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Mle, msl-1 and msl-3 are colocalized on the X chromosome. Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding.<ref>PMID:7768187</ref>
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[https://www.uniprot.org/uniprot/MSL3_DROME MSL3_DROME] The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Mle, msl-1 and msl-3 are colocalized on the X chromosome. Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding.<ref>PMID:7768187</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m9/3m9q_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m9/3m9q_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drome]]
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[[Category: Drosophila melanogaster]]
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[[Category: Huang, P]]
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[[Category: Large Structures]]
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[[Category: Khorasanizadeh, S]]
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[[Category: Huang P]]
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[[Category: Kim, D]]
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[[Category: Khorasanizadeh S]]
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[[Category: Rastinejad, F]]
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[[Category: Kim D]]
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[[Category: Aromatic cage]]
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[[Category: Rastinejad F]]
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[[Category: Chromodomain]]
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[[Category: Dna binding protein]]
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[[Category: Methyllysine recognition]]
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[[Category: Msl complex]]
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[[Category: Msl3]]
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[[Category: Transcription upregulation]]
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Current revision

Drosophila MSL3 chromodomain

PDB ID 3m9q

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