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4o1p

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==Crystal Structure of RNase L in complex with 2-5A and AMP-PNP==
==Crystal Structure of RNase L in complex with 2-5A and AMP-PNP==
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<StructureSection load='4o1p' size='340' side='right' caption='[[4o1p]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4o1p' size='340' side='right'caption='[[4o1p]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4o1p]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O1P FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4o1p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O1P FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=25L:[[(2R,3R,4R,5R)-5-(6-AMINOPURIN-9-YL)-4-[[(2R,3R,4R,5R)-5-(6-AMINOPURIN-9-YL)-4-[[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]OXY-3-HYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]OXY-3-HYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]+PHOSPHONO+HYDROGEN+PHOSPHATE'>25L</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4o1o|4o1o]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=25L:[[(2R,3R,4R,5R)-5-(6-AMINOPURIN-9-YL)-4-[[(2R,3R,4R,5R)-5-(6-AMINOPURIN-9-YL)-4-[[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]OXY-3-HYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]OXY-3-HYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]+PHOSPHONO+HYDROGEN+PHOSPHATE'>25L</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RNASEL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o1p OCA], [https://pdbe.org/4o1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o1p RCSB], [https://www.ebi.ac.uk/pdbsum/4o1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o1p ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o1p OCA], [http://pdbe.org/4o1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4o1p RCSB], [http://www.ebi.ac.uk/pdbsum/4o1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4o1p ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A5H025_PIG A5H025_PIG]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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*[[Temp|Temp]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pig]]
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[[Category: Large Structures]]
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[[Category: Ceccarelli, D F]]
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[[Category: Sus scrofa]]
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[[Category: Huang, H]]
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[[Category: Ceccarelli DF]]
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[[Category: Sicheri, F]]
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[[Category: Huang H]]
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[[Category: Zeqiraj, E]]
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[[Category: Sicheri F]]
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[[Category: 2-5a]]
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[[Category: Zeqiraj E]]
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[[Category: Ankyrin repeat-kinase-rnase]]
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[[Category: Hydrolase]]
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[[Category: Rna cleavage]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of RNase L in complex with 2-5A and AMP-PNP

PDB ID 4o1p

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