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2rot

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==Structure of chimeric variant of SH3 domain- SHH==
==Structure of chimeric variant of SH3 domain- SHH==
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<StructureSection load='2rot' size='340' side='right' caption='[[2rot]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2rot' size='340' side='right'caption='[[2rot]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2rot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ROT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ROT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2rot]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ROT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ROT FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rot OCA], [https://pdbe.org/2rot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rot RCSB], [https://www.ebi.ac.uk/pdbsum/2rot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rot ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rot OCA], [http://pdbe.org/2rot PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rot RCSB], [http://www.ebi.ac.uk/pdbsum/2rot PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rot ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK]] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
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[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/2rot_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/2rot_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Spectrin|Spectrin]]
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*[[Spectrin 3D structures|Spectrin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
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[[Category: Filimonov, V V]]
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[[Category: Large Structures]]
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[[Category: Gushchina, L V]]
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[[Category: Filimonov VV]]
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[[Category: Khristoforov, V S]]
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[[Category: Gushchina LV]]
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[[Category: Kudrevatykh, Y A]]
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[[Category: Khristoforov VS]]
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[[Category: Kutyshenko, N P]]
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[[Category: Kudrevatykh YA]]
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[[Category: Prokhorov, D A]]
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[[Category: Kutyshenko NP]]
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[[Category: Timchenko, M A]]
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[[Category: Prokhorov DA]]
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[[Category: Actin capping]]
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[[Category: Timchenko MA]]
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[[Category: Actin-binding]]
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[[Category: Alpha-spectrin]]
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[[Category: Calmodulin-binding]]
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[[Category: Chimeric protein]]
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[[Category: Cytoskeleton]]
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[[Category: Phosphoprotein]]
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[[Category: Protein binding]]
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[[Category: Sh3]]
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[[Category: Sh3 domain]]
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Current revision

Structure of chimeric variant of SH3 domain- SHH

PDB ID 2rot

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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