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3pqa

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==Crystal structure of glyceraldehyde-3-phosphate dehydrogenase GapN from Methanocaldococcus jannaschii DSM 2661==
==Crystal structure of glyceraldehyde-3-phosphate dehydrogenase GapN from Methanocaldococcus jannaschii DSM 2661==
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<StructureSection load='3pqa' size='340' side='right' caption='[[3pqa]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='3pqa' size='340' side='right'caption='[[3pqa]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pqa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PQA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pqa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PQA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ1411 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lactaldehyde_dehydrogenase Lactaldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.22 1.2.1.22] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pqa OCA], [https://pdbe.org/3pqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pqa RCSB], [https://www.ebi.ac.uk/pdbsum/3pqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pqa ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pqa OCA], [http://pdbe.org/3pqa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pqa RCSB], [http://www.ebi.ac.uk/pdbsum/3pqa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pqa ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LADH_METJA LADH_METJA]] Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. The substrate preference order is propionaldehyde > DL-lactaldehyde, DL-glyceraldehyde > crotonaldehyde > glycolaldehyde > acetaldehyde, acrolein > formaldehyde. No activity was observed towards methylglyoxal or glyceraldehyde-3-phosphate. Has a preference for NAD over NADP.
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[https://www.uniprot.org/uniprot/LADH_METJA LADH_METJA] Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate. The substrate preference order is propionaldehyde > DL-lactaldehyde, DL-glyceraldehyde > crotonaldehyde > glycolaldehyde > acetaldehyde, acrolein > formaldehyde. No activity was observed towards methylglyoxal or glyceraldehyde-3-phosphate. Has a preference for NAD over NADP.
==See Also==
==See Also==
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*[[Glyceraldehyde-3-Phosphate Dehydrogenase|Glyceraldehyde-3-Phosphate Dehydrogenase]]
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*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43067]]
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[[Category: Large Structures]]
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[[Category: Lactaldehyde dehydrogenase]]
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[[Category: Methanocaldococcus jannaschii]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Foti, R]]
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[[Category: Foti R]]
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[[Category: Garrett, S]]
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[[Category: Garrett S]]
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[[Category: Malashkevich, V N]]
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[[Category: Malashkevich VN]]
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[[Category: Structural genomic]]
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[[Category: Seidel R]]
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[[Category: Seidel, R]]
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[[Category: Toro R]]
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[[Category: Toro, R]]
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[[Category: Nysgrc]]
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[[Category: Oxidoreductase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-biology]]
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Current revision

Crystal structure of glyceraldehyde-3-phosphate dehydrogenase GapN from Methanocaldococcus jannaschii DSM 2661

PDB ID 3pqa

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