This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3sfv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (17:25, 1 November 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of the GDP-bound Rab1a S25N mutant in complex with the coiled-coil domain of LidA from Legionella pneumophila==
==Crystal structure of the GDP-bound Rab1a S25N mutant in complex with the coiled-coil domain of LidA from Legionella pneumophila==
-
<StructureSection load='3sfv' size='340' side='right' caption='[[3sfv]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
+
<StructureSection load='3sfv' size='340' side='right'caption='[[3sfv]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3sfv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Legpc Legpc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SFV FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3sfv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Legionella_pneumophila_str._Corby Legionella pneumophila str. Corby]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SFV FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAB1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), lidA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=400673 LEGPC])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sfv OCA], [http://pdbe.org/3sfv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sfv RCSB], [http://www.ebi.ac.uk/pdbsum/3sfv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sfv ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sfv OCA], [https://pdbe.org/3sfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sfv RCSB], [https://www.ebi.ac.uk/pdbsum/3sfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sfv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RAB1A_HUMAN RAB1A_HUMAN]] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
+
[https://www.uniprot.org/uniprot/RAB1A_HUMAN RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 3sfv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3sfv" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Legpc]]
+
[[Category: Large Structures]]
-
[[Category: Gu, L]]
+
[[Category: Legionella pneumophila str. Corby]]
-
[[Category: Li, B]]
+
[[Category: Gu L]]
-
[[Category: Lu, D]]
+
[[Category: Li B]]
-
[[Category: Xu, S]]
+
[[Category: Lu D]]
-
[[Category: Yin, K]]
+
[[Category: Xu S]]
-
[[Category: Zhang, H]]
+
[[Category: Yin K]]
-
[[Category: Zhu, D]]
+
[[Category: Zhang H]]
-
[[Category: Coiled-coil domain]]
+
[[Category: Zhu D]]
-
[[Category: Gdp binding]]
+
-
[[Category: Lida-rab complex]]
+
-
[[Category: Protein transport-protein binding complex]]
+
-
[[Category: Type iv effector protein from legionella]]
+

Current revision

Crystal structure of the GDP-bound Rab1a S25N mutant in complex with the coiled-coil domain of LidA from Legionella pneumophila

PDB ID 3sfv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools