4n0t

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==Core structure of the U6 small nuclear ribonucleoprotein at 1.7 Angstrom resolution==
==Core structure of the U6 small nuclear ribonucleoprotein at 1.7 Angstrom resolution==
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<StructureSection load='4n0t' size='340' side='right' caption='[[4n0t]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4n0t' size='340' side='right'caption='[[4n0t]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4n0t]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N0T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4n0t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N0T FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n0t OCA], [http://pdbe.org/4n0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n0t RCSB], [http://www.ebi.ac.uk/pdbsum/4n0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n0t ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n0t OCA], [https://pdbe.org/4n0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n0t RCSB], [https://www.ebi.ac.uk/pdbsum/4n0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n0t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRP24_YEAST PRP24_YEAST]] Binds preferentially to the U4/U6 hybrid snRNAs. Can stimulate the annealing of U4 and U6. Could participate in both the formation and disassembly of the U4/U6 hybrid during splicing.
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[https://www.uniprot.org/uniprot/PRP24_YEAST PRP24_YEAST] Binds preferentially to the U4/U6 hybrid snRNAs. Can stimulate the annealing of U4 and U6. Could participate in both the formation and disassembly of the U4/U6 hybrid during splicing.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Andrews, K L]]
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[[Category: Large Structures]]
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[[Category: Brow, D A]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Butcher, S E]]
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[[Category: Andrews KL]]
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[[Category: Curran, E C]]
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[[Category: Brow DA]]
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[[Category: Liao, H]]
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[[Category: Butcher SE]]
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[[Category: Montemayor, E J]]
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[[Category: Curran EC]]
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[[Category: Treba, C N]]
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[[Category: Liao H]]
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[[Category: Annealing u6 and u4 snrna]]
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[[Category: Montemayor EJ]]
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[[Category: Nucleus]]
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[[Category: Treba CN]]
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[[Category: Rna binding protein-rna complex]]
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[[Category: Spliceosomal ribonucleoprotein complex]]
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Current revision

Core structure of the U6 small nuclear ribonucleoprotein at 1.7 Angstrom resolution

PDB ID 4n0t

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