4lun
From Proteopedia
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| - | ==Structure of a | + | ==Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons== |
| - | <StructureSection load='4lun' size='340' side='right' caption='[[4lun]], [[Resolution|resolution]] 1.64Å' scene=''> | + | <StructureSection load='4lun' size='340' side='right'caption='[[4lun]], [[Resolution|resolution]] 1.64Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4lun]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUN OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4lun]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LUN FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.641Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lun OCA], [https://pdbe.org/4lun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lun RCSB], [https://www.ebi.ac.uk/pdbsum/4lun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lun ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NMD2_YEAST NMD2_YEAST] Involved in nonsense-mediated decay of mRNAs containing premature stop codons. It interacts, via its C-terminus, with NAM7/UPF1. Could be involved in determining the efficiency of translational termination or reinitiation or factors involved in the initial assembly of an initiation- and termination-competent mRNP. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Courreux | + | [[Category: Large Structures]] |
| - | [[Category: Fourati | + | [[Category: Saccharomyces cerevisiae S288C]] |
| - | [[Category: Graille | + | [[Category: Courreux PD]] |
| - | [[Category: He | + | [[Category: Fourati Z]] |
| - | [[Category: Jacobson | + | [[Category: Graille M]] |
| - | [[Category: Kervestin | + | [[Category: He F]] |
| - | [[Category: Millan | + | [[Category: Jacobson A]] |
| - | [[Category: Roy | + | [[Category: Kervestin S]] |
| - | + | [[Category: Millan C]] | |
| - | [[Category: Uson | + | [[Category: Roy B]] |
| - | [[Category: | + | [[Category: Uson I]] |
| - | + | [[Category: Van Tilbeurgh H]] | |
| - | + | ||
Current revision
Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons
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