3auy

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==Crystal structure of Rad50 bound to ADP==
==Crystal structure of Rad50 bound to ADP==
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<StructureSection load='3auy' size='340' side='right' caption='[[3auy]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='3auy' size='340' side='right'caption='[[3auy]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3auy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AUY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3auy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AUY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3aux|3aux]], [[3auz|3auz]], [[3av0|3av0]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rad50, MJ1322 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3auy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auy OCA], [https://pdbe.org/3auy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3auy RCSB], [https://www.ebi.ac.uk/pdbsum/3auy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3auy ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3auy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auy OCA], [http://pdbe.org/3auy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3auy RCSB], [http://www.ebi.ac.uk/pdbsum/3auy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3auy ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAD50_METJA RAD50_METJA]] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]
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[https://www.uniprot.org/uniprot/RAD50_METJA RAD50_METJA] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]
==See Also==
==See Also==
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*[[ATPase|ATPase]]
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*[[ATPase 3D structures|ATPase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43067]]
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[[Category: Large Structures]]
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[[Category: Cho, Y]]
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[[Category: Methanocaldococcus jannaschii]]
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[[Category: Lim, H S]]
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[[Category: Cho Y]]
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[[Category: Abc transporter atpase domain-like]]
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[[Category: Lim HS]]
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[[Category: Dna repair]]
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[[Category: Mre11]]
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[[Category: P-loop containing nucleoside triphosphate hydrolase]]
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[[Category: Recombination]]
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Crystal structure of Rad50 bound to ADP

PDB ID 3auy

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