4gjw

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==Structure of the tetramerization domain of Nipah virus phosphoprotein==
==Structure of the tetramerization domain of Nipah virus phosphoprotein==
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<StructureSection load='4gjw' size='340' side='right' caption='[[4gjw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='4gjw' size='340' side='right'caption='[[4gjw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gjw]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Nipav Nipav]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GJW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gjw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Henipavirus_nipahense Henipavirus nipahense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GJW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Nvgp2, P/V/C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=121791 NIPAV])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gjw OCA], [https://pdbe.org/4gjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gjw RCSB], [https://www.ebi.ac.uk/pdbsum/4gjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gjw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gjw OCA], [http://pdbe.org/4gjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gjw RCSB], [http://www.ebi.ac.uk/pdbsum/4gjw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gjw ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PHOSP_NIPAV PHOSP_NIPAV]] Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity). May play a role to prevent the establishment of cellular antiviral state by binding to host STAT1 in the cytoplasm. This activity is not as strong as that of V and W.
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[https://www.uniprot.org/uniprot/PHOSP_NIPAV PHOSP_NIPAV] Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity). May play a role to prevent the establishment of cellular antiviral state by binding to host STAT1 in the cytoplasm. This activity is not as strong as that of V and W.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Nipav]]
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[[Category: Henipavirus nipahense]]
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[[Category: Jamin, M]]
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[[Category: Large Structures]]
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[[Category: Tarbouriech, N]]
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[[Category: Jamin M]]
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[[Category: Yabukarski, F]]
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[[Category: Tarbouriech N]]
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[[Category: Helix coiled-coil]]
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[[Category: Yabukarski F]]
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[[Category: Nucleoprotein]]
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[[Category: Polymerase]]
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[[Category: Polymerase cofactor]]
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[[Category: Transcription]]
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Current revision

Structure of the tetramerization domain of Nipah virus phosphoprotein

PDB ID 4gjw

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