4bs6
From Proteopedia
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==MOUSE CATHEPSIN S WITH COVALENT LIGAND== | ==MOUSE CATHEPSIN S WITH COVALENT LIGAND== | ||
- | <StructureSection load='4bs6' size='340' side='right' caption='[[4bs6]], [[Resolution|resolution]] 1.20Å' scene=''> | + | <StructureSection load='4bs6' size='340' side='right'caption='[[4bs6]], [[Resolution|resolution]] 1.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4bs6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BS6 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4bs6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BS6 FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JG7:(2S,4R)-4-[2-CHLORANYL-4-(4-ETHYLPIPERAZIN-1-YL)PHENYL]SULFONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]-1-[1-(TRIFLUOROMETHYL)CYCLOPROPYL]CARBONYL-PYRROLIDINE-2-CARBOXAMIDE'>JG7</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JG7:(2S,4R)-4-[2-CHLORANYL-4-(4-ETHYLPIPERAZIN-1-YL)PHENYL]SULFONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]-1-[1-(TRIFLUOROMETHYL)CYCLOPROPYL]CARBONYL-PYRROLIDINE-2-CARBOXAMIDE'>JG7</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bs6 OCA], [https://pdbe.org/4bs6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bs6 RCSB], [https://www.ebi.ac.uk/pdbsum/4bs6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bs6 ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/CATS_MOUSE CATS_MOUSE] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. |
==See Also== | ==See Also== | ||
- | *[[Cathepsin|Cathepsin]] | + | *[[Cathepsin 3D structures|Cathepsin 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Banner | + | [[Category: Mus musculus]] |
- | [[Category: Benz | + | [[Category: Banner DW]] |
- | [[Category: Gsell | + | [[Category: Benz J]] |
- | [[Category: Haap | + | [[Category: Gsell B]] |
- | [[Category: Ruf | + | [[Category: Haap W]] |
- | [[Category: Stihle | + | [[Category: Ruf A]] |
- | + | [[Category: Stihle M]] | |
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Current revision
MOUSE CATHEPSIN S WITH COVALENT LIGAND
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Categories: Large Structures | Mus musculus | Banner DW | Benz J | Gsell B | Haap W | Ruf A | Stihle M