2vsg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:32, 17 October 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
==A Structural Motif in the Variant Surface Glycoproteins of Trypanosoma Brucei==
==A Structural Motif in the Variant Surface Glycoproteins of Trypanosoma Brucei==
-
<StructureSection load='2vsg' size='340' side='right' caption='[[2vsg]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+
<StructureSection load='2vsg' size='340' side='right'caption='[[2vsg]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2vsg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VSG FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2vsg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VSG FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vsg|1vsg]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsg OCA], [http://pdbe.org/2vsg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vsg RCSB], [http://www.ebi.ac.uk/pdbsum/2vsg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsg ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsg OCA], [https://pdbe.org/2vsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vsg RCSB], [https://www.ebi.ac.uk/pdbsum/2vsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/VSI4_TRYBB VSI4_TRYBB]] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
+
[https://www.uniprot.org/uniprot/VSI4_TRYBB VSI4_TRYBB] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vsg_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vsg_consurf.spt"</scriptWhenChecked>
-
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
Line 32: Line 32:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
-
[[Category: Blum, M L]]
+
[[Category: Blum ML]]
-
[[Category: Down, J A]]
+
[[Category: Down JA]]
-
[[Category: Freymann, D M]]
+
[[Category: Freymann DM]]
-
[[Category: Metcalf, P]]
+
[[Category: Metcalf P]]
-
[[Category: Wiley, D C]]
+
[[Category: Wiley DC]]
-
[[Category: Antigenic variation]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Trypanosome]]
+
-
[[Category: Vsg]]
+

Current revision

A Structural Motif in the Variant Surface Glycoproteins of Trypanosoma Brucei

PDB ID 2vsg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2vsg"
Personal tools