3dxy

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==Crystal structure of EcTrmB in complex with SAM==
==Crystal structure of EcTrmB in complex with SAM==
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<StructureSection load='3dxy' size='340' side='right' caption='[[3dxy]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='3dxy' size='340' side='right'caption='[[3dxy]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3dxy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DXY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3dxy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DXY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dxx|3dxx]], [[3dxz|3dxz]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dxy OCA], [https://pdbe.org/3dxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dxy RCSB], [https://www.ebi.ac.uk/pdbsum/3dxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dxy ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(46)-N(7))-methyltransferase tRNA (guanine(46)-N(7))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.33 2.1.1.33] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dxy OCA], [http://pdbe.org/3dxy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dxy RCSB], [http://www.ebi.ac.uk/pdbsum/3dxy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dxy ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRMB_ECOLI TRMB_ECOLI]] Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
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[https://www.uniprot.org/uniprot/TRMB_ECOLI TRMB_ECOLI] Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/3dxy_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/3dxy_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[TRNA methyltransferase|TRNA methyltransferase]]
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Gao, Y X]]
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[[Category: Large Structures]]
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[[Category: Liu, Q]]
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[[Category: Gao YX]]
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[[Category: Niu, L W]]
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[[Category: Liu Q]]
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[[Category: Teng, M K]]
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[[Category: Niu LW]]
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[[Category: Zhou, H H]]
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[[Category: Teng MK]]
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[[Category: Methyltransferase]]
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[[Category: Zhou HH]]
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[[Category: Rossmann fold methyltransferase]]
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[[Category: S-adenosyl-l-methionine]]
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[[Category: Transferase]]
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[[Category: Trna modification]]
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[[Category: Trna processing]]
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Current revision

Crystal structure of EcTrmB in complex with SAM

PDB ID 3dxy

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