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3jvm

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==Crystal structure of bromodomain 2 of mouse Brd4==
==Crystal structure of bromodomain 2 of mouse Brd4==
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<StructureSection load='3jvm' size='340' side='right' caption='[[3jvm]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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<StructureSection load='3jvm' size='340' side='right'caption='[[3jvm]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3jvm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JVM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3jvm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JVM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jvj|3jvj]], [[3jvk|3jvk]], [[3jvl|3jvl]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Brd4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jvm OCA], [https://pdbe.org/3jvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jvm RCSB], [https://www.ebi.ac.uk/pdbsum/3jvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jvm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jvm OCA], [http://pdbe.org/3jvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jvm RCSB], [http://www.ebi.ac.uk/pdbsum/3jvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jvm ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BRD4_MOUSE BRD4_MOUSE]] Plays a role in a process governing chromosomal dynamics during mitosis.<ref>PMID:10938129</ref>
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[https://www.uniprot.org/uniprot/BRD4_MOUSE BRD4_MOUSE] Plays a role in a process governing chromosomal dynamics during mitosis.<ref>PMID:10938129</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/3jvm_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/3jvm_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Bromodomain-containing protein|Bromodomain-containing protein]]
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*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Blankenfeldt, W]]
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[[Category: Mus musculus]]
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[[Category: Geyer, M]]
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[[Category: Blankenfeldt W]]
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[[Category: Vollmuth, F]]
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[[Category: Geyer M]]
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[[Category: Alpha helical]]
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[[Category: Vollmuth F]]
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[[Category: Bromodomain]]
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[[Category: N-acetyl lysine binding domain]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of bromodomain 2 of mouse Brd4

PDB ID 3jvm

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