4nmh
From Proteopedia
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==11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one== | ==11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one== | ||
- | <StructureSection load='4nmh' size='340' side='right' caption='[[4nmh]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='4nmh' size='340' side='right'caption='[[4nmh]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4nmh]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4nmh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NMH FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2KG:(4S)-4-(2-METHOXYPHENYL)-3,3-DIMETHYL-1-[3-(METHYLSULFONYL)PHENYL]AZETIDIN-2-ONE'>2KG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2KG:(4S)-4-(2-METHOXYPHENYL)-3,3-DIMETHYL-1-[3-(METHYLSULFONYL)PHENYL]AZETIDIN-2-ONE'>2KG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nmh OCA], [https://pdbe.org/4nmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nmh RCSB], [https://www.ebi.ac.uk/pdbsum/4nmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nmh ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/DHI1_MOUSE DHI1_MOUSE] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. |
==See Also== | ==See Also== | ||
- | *[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | + | *[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Mus musculus]] |
- | [[Category: Augustin | + | [[Category: Augustin M]] |
- | [[Category: Blake | + | [[Category: Blake C]] |
- | [[Category: Ertan | + | [[Category: Ertan A]] |
- | [[Category: Gerhardt | + | [[Category: Gerhardt S]] |
- | [[Category: Kilgour | + | [[Category: Kilgour EK]] |
- | [[Category: Krapp | + | [[Category: Krapp S]] |
- | [[Category: McCoull | + | [[Category: McCoull W]] |
- | [[Category: Moore | + | [[Category: Moore JE]] |
- | [[Category: Newcombe | + | [[Category: Newcombe NJ]] |
- | [[Category: Ogg | + | [[Category: Ogg DJ]] |
- | [[Category: Packer | + | [[Category: Packer MJ]] |
- | [[Category: Rees | + | [[Category: Rees A]] |
- | [[Category: Revill | + | [[Category: Revill J]] |
- | [[Category: Scott | + | [[Category: Scott JS]] |
- | [[Category: Selmi | + | [[Category: Selmi N]] |
- | [[Category: Steinbacher | + | [[Category: Steinbacher S]] |
- | [[Category: Whittamore | + | [[Category: Whittamore PRO]] |
- | + | ||
- | + |
Current revision
11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one
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Categories: Large Structures | Mus musculus | Augustin M | Blake C | Ertan A | Gerhardt S | Kilgour EK | Krapp S | McCoull W | Moore JE | Newcombe NJ | Ogg DJ | Packer MJ | Rees A | Revill J | Scott JS | Selmi N | Steinbacher S | Whittamore PRO