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3ms5
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==Crystal Structure of Human gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 (BBOX1)== | ==Crystal Structure of Human gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 (BBOX1)== | ||
| - | <StructureSection load='3ms5' size='340' side='right' caption='[[3ms5]], [[Resolution|resolution]] 1.82Å' scene=''> | + | <StructureSection load='3ms5' size='340' side='right'caption='[[3ms5]], [[Resolution|resolution]] 1.82Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ms5]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ms5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MS5 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=REE:2-(2-CARBOXYETHYL)-1,1,1-TRIMETHYLDIAZANIUM'>REE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=REE:2-(2-CARBOXYETHYL)-1,1,1-TRIMETHYLDIAZANIUM'>REE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ms5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ms5 OCA], [https://pdbe.org/3ms5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ms5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ms5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ms5 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BODG_HUMAN BODG_HUMAN] Catalyzes the formation of L-carnitine from gamma-butyrobetaine. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/3ms5_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/3ms5_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ms5 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ms5 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Dioxygenase 3D structures|Dioxygenase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Claridge | + | [[Category: Claridge TDW]] |
| - | + | [[Category: Edwards A]] | |
| - | [[Category: Edwards | + | [[Category: Filippakopoulos P]] |
| - | [[Category: Filippakopoulos | + | [[Category: Henry L]] |
| - | [[Category: Henry | + | [[Category: Kavanagh KL]] |
| - | [[Category: Kavanagh | + | [[Category: Kochan G]] |
| - | [[Category: Kochan | + | [[Category: Krojer T]] |
| - | [[Category: Krojer | + | [[Category: Leung IKH]] |
| - | [[Category: Leung | + | [[Category: McDonough MA]] |
| - | [[Category: McDonough | + | [[Category: Muniz J]] |
| - | [[Category: Muniz | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Pilka E]] |
| - | [[Category: Pilka | + | [[Category: Schofield CJ]] |
| - | + | [[Category: Ugochukwu E]] | |
| - | [[Category: Schofield | + | [[Category: Weigelt J]] |
| - | [[Category: Ugochukwu | + | [[Category: Von Delft F]] |
| - | [[Category: Weigelt | + | |
| - | [[Category: | + | |
| - | + | ||
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Current revision
Crystal Structure of Human gamma-butyrobetaine,2-oxoglutarate dioxygenase 1 (BBOX1)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Claridge TDW | Edwards A | Filippakopoulos P | Henry L | Kavanagh KL | Kochan G | Krojer T | Leung IKH | McDonough MA | Muniz J | Oppermann U | Pilka E | Schofield CJ | Ugochukwu E | Weigelt J | Von Delft F
