4e5o

<StructureSection load='4e5o' size='340' side='right' caption='[[4e5o]], [[Resolution|resolution]] 1.70&Aring;' scene=''>

<table><tr><td colspan='2'>[[4e5o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ihh 3ihh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E5O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E5O FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ihi|3ihi]]</td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tyms ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e5o OCA], [http://pdbe.org/4e5o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e5o RCSB], [http://www.ebi.ac.uk/pdbsum/4e5o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e5o ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).

*[[Thymidylate synthase|Thymidylate synthase]]

[[Category: Lk3 transgenic mice]]

[[Category: Thymidylate synthase]]

[[Category: Ciesla, J]]

[[Category: Dowiercial, A]]

[[Category: Fraczyk, T]]

[[Category: Jarmula, A]]

[[Category: Rode, W]]

[[Category: Rypniewski, W]]

[[Category: Sokolowska, M]]

[[Category: Transferase]]