4ami

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:30, 20 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
==Turkey beta1 adrenergic receptor with stabilising mutations and bound biased agonist bucindolol==
==Turkey beta1 adrenergic receptor with stabilising mutations and bound biased agonist bucindolol==
-
<StructureSection load='4ami' size='340' side='right' caption='[[4ami]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
+
<StructureSection load='4ami' size='340' side='right'caption='[[4ami]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4ami]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Common_turkey Common turkey]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AMI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AMI FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4ami]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AMI FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=G90:2-[(2S)-3-[[1-(1H-INDOL-3-YL)-2-METHYL-PROPAN-2-YL]AMINO]-2-OXIDANYL-PROPOXY]BENZENECARBONITRILE'>G90</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dep|1dep]], [[2vt4|2vt4]], [[2y00|2y00]], [[2y01|2y01]], [[2y02|2y02]], [[2y03|2y03]], [[2y04|2y04]], [[2ycw|2ycw]], [[2ycx|2ycx]], [[2ycy|2ycy]], [[2ycz|2ycz]], [[4amj|4amj]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=G90:2-[(2S)-3-[[1-(1H-INDOL-3-YL)-2-METHYL-PROPAN-2-YL]AMINO]-2-OXIDANYL-PROPOXY]BENZENECARBONITRILE'>G90</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ami FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ami OCA], [http://pdbe.org/4ami PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ami RCSB], [http://www.ebi.ac.uk/pdbsum/4ami PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ami ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ami FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ami OCA], [https://pdbe.org/4ami PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ami RCSB], [https://www.ebi.ac.uk/pdbsum/4ami PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ami ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA]] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
+
[https://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 21:
==See Also==
==See Also==
-
*[[Adrenergic receptor|Adrenergic receptor]]
+
*[[Adrenergic receptor 3D structures|Adrenergic receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Common turkey]]
+
[[Category: Large Structures]]
-
[[Category: Edwards, P C]]
+
[[Category: Meleagris gallopavo]]
-
[[Category: Leslie, A G]]
+
[[Category: Edwards PC]]
-
[[Category: Tate, C G]]
+
[[Category: Leslie AG]]
-
[[Category: Warne, T]]
+
[[Category: Tate CG]]
-
[[Category: 7tmr beta1-adrenoceptor]]
+
[[Category: Warne T]]
-
[[Category: Biased agonist]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Stabilising mutation]]
+

Current revision

Turkey beta1 adrenergic receptor with stabilising mutations and bound biased agonist bucindolol

PDB ID 4ami

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ami"
Personal tools