3e7x

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:19, 1 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of DLTA: implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains==
==Crystal structure of DLTA: implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains==
-
<StructureSection load='3e7x' size='340' side='right' caption='[[3e7x]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+
<StructureSection load='3e7x' size='340' side='right'caption='[[3e7x]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3e7x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E7X FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3e7x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E7X FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1amu|1amu]], [[1md9|1md9]], [[2dls|2dls]], [[1ba3|1ba3]], [[1pg4|1pg4]], [[1hqb|1hqb]], [[3e7w|3e7w]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dltA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e7x OCA], [https://pdbe.org/3e7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e7x RCSB], [https://www.ebi.ac.uk/pdbsum/3e7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e7x ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-alanine--poly(phosphoribitol)_ligase D-alanine--poly(phosphoribitol) ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.13 6.1.1.13] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e7x OCA], [http://pdbe.org/3e7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e7x RCSB], [http://www.ebi.ac.uk/pdbsum/3e7x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3e7x ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DLTA_BACSU DLTA_BACSU]] Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp.
+
[https://www.uniprot.org/uniprot/DLTA_BACSU DLTA_BACSU] Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/3e7x_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e7/3e7x_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 35: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bacillus globigii migula 1900]]
+
[[Category: Bacillus subtilis]]
-
[[Category: Marahiel, M A]]
+
[[Category: Large Structures]]
-
[[Category: May, J J]]
+
[[Category: Marahiel MA]]
-
[[Category: Neumann, P]]
+
[[Category: May JJ]]
-
[[Category: Stubbs, M T]]
+
[[Category: Neumann P]]
-
[[Category: Yonus, H]]
+
[[Category: Stubbs MT]]
-
[[Category: Zimmermann, S]]
+
[[Category: Yonus H]]
-
[[Category: Adenylation domain]]
+
[[Category: Zimmermann S]]
-
[[Category: Amp]]
+
-
[[Category: D-alanine-dalanyl]]
+
-
[[Category: D-alanylation]]
+
-
[[Category: Dlta]]
+
-
[[Category: Ligase]]
+
-
[[Category: Non-ribosomal peptide synthetase]]
+
-
[[Category: Nrp]]
+

Current revision

Crystal structure of DLTA: implications for the reaction mechanism of non-ribosomal peptide synthetase (NRPS) adenylation domains

PDB ID 3e7x

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3e7x"
Personal tools