2zpu

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==Crystal Structure of Modified Serine Racemase from S.pombe.==
==Crystal Structure of Modified Serine Racemase from S.pombe.==
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<StructureSection load='2zpu' size='340' side='right' caption='[[2zpu]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='2zpu' size='340' side='right'caption='[[2zpu]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZPU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZPU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PDD:N-(5-PHOSPHOPYRIDOXYL)-D-ALANINE'>PDD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPCC320.14, SPCC330.15c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 CBS 356])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PDD:N-(5-PHOSPHOPYRIDOXYL)-D-ALANINE'>PDD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serine_racemase Serine racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.18 5.1.1.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zpu OCA], [https://pdbe.org/2zpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zpu RCSB], [https://www.ebi.ac.uk/pdbsum/2zpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zpu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zpu OCA], [http://pdbe.org/2zpu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zpu RCSB], [http://www.ebi.ac.uk/pdbsum/2zpu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zpu ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SRR_SCHPO SRR_SCHPO]] Catalyzes the synthesis of D-serine from L-serine. Has dehydratase activity towards both L-serine and D-serine.<ref>PMID:19640845</ref>
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[https://www.uniprot.org/uniprot/SRR_SCHPO SRR_SCHPO] Catalyzes the synthesis of D-serine from L-serine. Has dehydratase activity towards both L-serine and D-serine.<ref>PMID:19640845</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/2zpu_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/2zpu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cbs 356]]
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[[Category: Large Structures]]
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[[Category: Serine racemase]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: Goto, M]]
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[[Category: Goto M]]
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[[Category: Isomerase]]
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[[Category: Lyase]]
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[[Category: Plp-dependent]]
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[[Category: Pyridoxal phosphate]]
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Current revision

Crystal Structure of Modified Serine Racemase from S.pombe.

PDB ID 2zpu

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