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4e6x

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==ClbP in complex boron-based inhibitor==
==ClbP in complex boron-based inhibitor==
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<StructureSection load='4e6x' size='340' side='right' caption='[[4e6x]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
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<StructureSection load='4e6x' size='340' side='right'caption='[[4e6x]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4e6x]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_o6 Escherichia coli o6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E6X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4e6x]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O6 Escherichia coli O6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E6X FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0NG:({[(CHLOROMETHYL)SULFONYL]AMINO}METHYL)BORONIC+ACID'>0NG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o3v|3o3v]], [[4e6w|4e6w]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0NG:({[(CHLOROMETHYL)SULFONYL]AMINO}METHYL)BORONIC+ACID'>0NG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">c2452, IHE3034 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=217992 Escherichia coli O6])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e6x OCA], [https://pdbe.org/4e6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e6x RCSB], [https://www.ebi.ac.uk/pdbsum/4e6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e6x ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e6x OCA], [http://pdbe.org/4e6x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4e6x RCSB], [http://www.ebi.ac.uk/pdbsum/4e6x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4e6x ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0H2V8D3_ECOL6 A0A0H2V8D3_ECOL6] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.[ARBA:ARBA00003808]
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Escherichia coli O6]]
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[[Category: Escherichia coli o6]]
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[[Category: Large Structures]]
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[[Category: Bonnet, R]]
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[[Category: Bonnet R]]
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[[Category: Cougnoux, A]]
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[[Category: Cougnoux A]]
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[[Category: Delmas, J]]
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[[Category: Delmas J]]
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[[Category: Alpha/beta]]
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[[Category: Disulfide bridge]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Peptidase]]
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Current revision

ClbP in complex boron-based inhibitor

PDB ID 4e6x

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