3oy2

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==Crystal structure of a putative glycosyltransferase from Paramecium bursaria Chlorella virus NY2A==
==Crystal structure of a putative glycosyltransferase from Paramecium bursaria Chlorella virus NY2A==
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<StructureSection load='3oy2' size='340' side='right' caption='[[3oy2]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
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<StructureSection load='3oy2' size='340' side='right'caption='[[3oy2]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3oy2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlorella_virus_cv-ny-2a Chlorella virus cv-ny-2a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OY2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3oy2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paramecium_bursaria_Chlorella_virus_NY2A Paramecium bursaria Chlorella virus NY2A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OY2 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3oy7|3oy7]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">B736L, NY2A_B736L ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46021 Chlorella virus CV-NY-2A])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oy2 OCA], [https://pdbe.org/3oy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oy2 RCSB], [https://www.ebi.ac.uk/pdbsum/3oy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oy2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oy2 OCA], [http://pdbe.org/3oy2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3oy2 RCSB], [http://www.ebi.ac.uk/pdbsum/3oy2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3oy2 ProSAT]</span></td></tr>
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</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/A7IXR1_PBCVN A7IXR1_PBCVN]
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The chloroviruses (family Phycodnaviridae), unlike most viruses, encode some, if not most, of the enzymes involved in the glycosylation of their structural proteins. Annotation of the gene product B736L from chlorovirus NY-2A suggests that it is a glycosyltransferase. The structure of the recombinantly expressed B736L protein was determined by X-ray crystallography to 2.3-A resolution, and the protein was shown to have two nucleotide-binding folds like other glycosyltransferase type B enzymes. This is the second structure of a chlorovirus-encoded glycosyltransferase and the first structure of a chlorovirus type B enzyme to be determined. B736L is a retaining enzyme and belongs to glycosyltransferase family 4. The donor substrate was identified as GDP-mannose by isothermal titration calorimetry and was shown to bind into the cleft between the two domains in the protein. The active form of the enzyme is probably a dimer in which the active centers are separated by about 40 A.
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Crystal structure of a virus-encoded putative glycosyltransferase.,Xiang Y, Baxa U, Zhang Y, Steven AC, Lewis GL, Van Etten JL, Rossmann MG J Virol. 2010 Dec;84(23):12265-73. Epub 2010 Sep 22. PMID:20861263<ref>PMID:20861263</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3oy2" style="background-color:#fffaf0;"></div>
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==See Also==
==See Also==
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*[[Glycosyltransferase|Glycosyltransferase]]
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chlorella virus cv-ny-2a]]
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[[Category: Large Structures]]
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[[Category: Rossmann, M G]]
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[[Category: Paramecium bursaria Chlorella virus NY2A]]
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[[Category: Xiang, Y]]
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[[Category: Rossmann MG]]
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[[Category: Gdp-mannose]]
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[[Category: Xiang Y]]
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[[Category: Glycosyltransferase]]
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[[Category: Rossmann fold]]
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[[Category: Sugar]]
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[[Category: Transferase]]
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[[Category: Viral protein]]
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[[Category: Virus capsid protein]]
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Current revision

Crystal structure of a putative glycosyltransferase from Paramecium bursaria Chlorella virus NY2A

PDB ID 3oy2

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