This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4ian

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:54, 9 November 2022) (edit) (undo)
 
Line 1: Line 1:
==Crystal Structure of apo Human PRPF4B kinase domain==
==Crystal Structure of apo Human PRPF4B kinase domain==
-
<StructureSection load='4ian' size='340' side='right' caption='[[4ian]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
+
<StructureSection load='4ian' size='340' side='right'caption='[[4ian]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4ian]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IAN FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4ian]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IAN FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ian FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ian OCA], [https://pdbe.org/4ian PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ian RCSB], [https://www.ebi.ac.uk/pdbsum/4ian PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ian ProSAT]</span></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ifc|4ifc]], [[4iir|4iir]], [[4ijp|4ijp]]</td></tr>
+
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA0536, PRP4, PRP4H, PRP4K, PRPF4B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ian FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ian OCA], [http://pdbe.org/4ian PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ian RCSB], [http://www.ebi.ac.uk/pdbsum/4ian PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ian ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN]] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
+
[https://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 26: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Non-specific serine/threonine protein kinase]]
+
[[Category: Large Structures]]
-
[[Category: Chen, X]]
+
[[Category: Chen X]]
-
[[Category: Haas, K]]
+
[[Category: Haas K]]
-
[[Category: McLean, L]]
+
[[Category: McLean L]]
-
[[Category: Mechin, I]]
+
[[Category: Mechin I]]
-
[[Category: Zhang, Y]]
+
[[Category: Zhang Y]]
-
[[Category: Kinase]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal Structure of apo Human PRPF4B kinase domain

PDB ID 4ian

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ian"
Personal tools