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4bji

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==Sfc1-DBD==
==Sfc1-DBD==
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<StructureSection load='4bji' size='340' side='right' caption='[[4bji]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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<StructureSection load='4bji' size='340' side='right'caption='[[4bji]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4bji]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_927 Schizosaccharomyces pombe 927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BJI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BJI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4bji]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_927 Schizosaccharomyces pombe 927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BJI FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bjj|4bjj]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4bjj|4bjj]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bji OCA], [http://pdbe.org/4bji PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bji RCSB], [http://www.ebi.ac.uk/pdbsum/4bji PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bji ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bji OCA], [https://pdbe.org/4bji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bji RCSB], [https://www.ebi.ac.uk/pdbsum/4bji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bji ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SFC1_SCHPO SFC1_SCHPO]] TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes. Participates in the interconnection of tauA with tauB via its contacts with sfc3 and sfc6. Serves as a scaffold critical for tauA-DNA spatial configuration and tauB-DNA stability. Localizes to chromatin insulator sequence without recruiting RNA polymerase III and plays a role in nuclear organization.<ref>PMID:10906331</ref> <ref>PMID:16751097</ref>
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[[https://www.uniprot.org/uniprot/SFC1_SCHPO SFC1_SCHPO]] TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes. Participates in the interconnection of tauA with tauB via its contacts with sfc3 and sfc6. Serves as a scaffold critical for tauA-DNA spatial configuration and tauB-DNA stability. Localizes to chromatin insulator sequence without recruiting RNA polymerase III and plays a role in nuclear organization.<ref>PMID:10906331</ref> <ref>PMID:16751097</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4bji" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4bji" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Transcription factor tau|Transcription factor tau]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe 927]]
[[Category: Schizosaccharomyces pombe 927]]
[[Category: Baudin, F]]
[[Category: Baudin, F]]

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Sfc1-DBD

PDB ID 4bji

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