3a7n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:14, 1 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of uracil-DNA glycosylase from Mycobacterium tuberculosis==
==Crystal structure of uracil-DNA glycosylase from Mycobacterium tuberculosis==
-
<StructureSection load='3a7n' size='340' side='right' caption='[[3a7n]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
+
<StructureSection load='3a7n' size='340' side='right'caption='[[3a7n]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3a7n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A7N FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3a7n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A7N FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zhx|2zhx]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ung, Rv2976c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a7n OCA], [https://pdbe.org/3a7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a7n RCSB], [https://www.ebi.ac.uk/pdbsum/3a7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a7n ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_nucleosidase Uridine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.3 3.2.2.3] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a7n OCA], [http://pdbe.org/3a7n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a7n RCSB], [http://www.ebi.ac.uk/pdbsum/3a7n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a7n ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/UNG_MYCTU UNG_MYCTU]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).
+
[https://www.uniprot.org/uniprot/UNG_MYCTU UNG_MYCTU] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a7/3a7n_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a7/3a7n_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 33: Line 31:
==See Also==
==See Also==
-
*[[DNA glycosylase|DNA glycosylase]]
+
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
-
*[[Uracil-DNA glycosylase|Uracil-DNA glycosylase]]
+
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Myctu]]
+
[[Category: Large Structures]]
-
[[Category: Uridine nucleosidase]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Kaushal, P S]]
+
[[Category: Kaushal PS]]
-
[[Category: Talawar, R K]]
+
[[Category: Talawar RK]]
-
[[Category: Varshney, U]]
+
[[Category: Varshney U]]
-
[[Category: Vijayan, M]]
+
[[Category: Vijayan M]]
-
[[Category: Citrate as protein ligand]]
+
-
[[Category: Dna damage]]
+
-
[[Category: Dna repair]]
+
-
[[Category: Glycosidase]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Inhibitor design]]
+
-
[[Category: Ligand binding]]
+
-
[[Category: Ung-dna complex]]
+
-
[[Category: Ung-ugi interaction]]
+

Current revision

Crystal structure of uracil-DNA glycosylase from Mycobacterium tuberculosis

PDB ID 3a7n

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3a7n"
Personal tools