This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4hur

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:11, 20 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus in complex with acetyl coenzyme A==
==Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus in complex with acetyl coenzyme A==
-
<StructureSection load='4hur' size='340' side='right' caption='[[4hur]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
+
<StructureSection load='4hur' size='340' side='right'caption='[[4hur]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4hur]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUR FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4hur]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HUR FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hus|4hus]], [[4e8l|4e8l]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vat ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hur OCA], [https://pdbe.org/4hur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hur RCSB], [https://www.ebi.ac.uk/pdbsum/4hur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hur ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hur OCA], [http://pdbe.org/4hur PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hur RCSB], [http://www.ebi.ac.uk/pdbsum/4hur PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hur ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/VATA_STAAU VATA_STAAU]] Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics.
+
[https://www.uniprot.org/uniprot/VATA_STAAU VATA_STAAU] Inactivates the A compounds of virginiamycin-like antibiotics, thus providing resistance to these antibiotics.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Anderson, W F]]
+
[[Category: Large Structures]]
-
[[Category: Structural genomic]]
+
[[Category: Staphylococcus aureus]]
-
[[Category: Courvalin, P]]
+
[[Category: Anderson WF]]
-
[[Category: Evdokimova, E]]
+
[[Category: Courvalin P]]
-
[[Category: Krishnamoorthy, M]]
+
[[Category: Di Leo R]]
-
[[Category: Leo, R Di]]
+
[[Category: Evdokimova E]]
-
[[Category: Minasov, G]]
+
[[Category: Krishnamoorthy M]]
-
[[Category: Savchenko, A]]
+
[[Category: Minasov G]]
-
[[Category: Stogios, P J]]
+
[[Category: Savchenko A]]
-
[[Category: Wawrzak, Z]]
+
[[Category: Stogios PJ]]
-
[[Category: Yim, V]]
+
[[Category: Wawrzak Z]]
-
[[Category: Acetyl coenzyme some]]
+
[[Category: Yim V]]
-
[[Category: Antibiotic resistance]]
+
-
[[Category: Coenzyme some]]
+
-
[[Category: Dalfopristin]]
+
-
[[Category: Hexapeptide repeat acyltransferase]]
+
-
[[Category: Intracellular]]
+
-
[[Category: National institute of allergy and infectious disease]]
+
-
[[Category: Niaid]]
+
-
[[Category: Streptogramin some]]
+
-
[[Category: Streptogramin group a antibiotic acetyltransferase]]
+
-
[[Category: Streptogramin group a antibiotic]]
+
-
[[Category: Transferase]]
+
-
[[Category: Virginiamycin m1]]
+

Current revision

Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus in complex with acetyl coenzyme A

PDB ID 4hur

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4hur"
Personal tools