3txk

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==HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant at pH 6.5==
==HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant at pH 6.5==
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<StructureSection load='3txk' size='340' side='right' caption='[[3txk]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='3txk' size='340' side='right'caption='[[3txk]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3txk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TXK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TXK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3txk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TXK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i6z|2i6z]], [[3txb|3txb]], [[3txc|3txc]], [[3txd|3txd]], [[3txe|3txe]], [[3txf|3txf]], [[3txg|3txg]], [[3txh|3txh]], [[3txi|3txi]], [[3txj|3txj]], [[3txl|3txl]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3txk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3txk OCA], [https://pdbe.org/3txk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3txk RCSB], [https://www.ebi.ac.uk/pdbsum/3txk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3txk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3txk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3txk OCA], [http://pdbe.org/3txk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3txk RCSB], [http://www.ebi.ac.uk/pdbsum/3txk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3txk ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Helliwell, J R]]
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[[Category: Helliwell JR]]
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[[Category: Kroon-Batenburg, L M.J]]
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[[Category: Kroon-Batenburg LMJ]]
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[[Category: Schreurs, A M.M]]
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[[Category: Schreurs AMM]]
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[[Category: Tanley, S W.M]]
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[[Category: Tanley SWM]]
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[[Category: Bacterial cell wall lysis]]
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[[Category: Hydrolase]]
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Current revision

HEWL co-crystallization with cisplatin in DMSO media with paratone as the cryoprotectant at pH 6.5

PDB ID 3txk

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