2wc9

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==CRYSTAL STRUCTURE OF THE G2P (LARGE TERMINASE) NUCLEASE DOMAIN FROM THE BACTERIOPHAGE SPP1 WITH BOUND MN==
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==Crystal structure of the g2p (large terminase) nuclease domain from the bacteriophage SPP1 with bound Mn==
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<StructureSection load='2wc9' size='340' side='right' caption='[[2wc9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='2wc9' size='340' side='right'caption='[[2wc9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wc9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpspp Bpspp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WC9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wc9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_phage_SPP1 Bacillus phage SPP1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WC9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wbn|2wbn]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc9 OCA], [https://pdbe.org/2wc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wc9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wc9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc9 OCA], [http://pdbe.org/2wc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wc9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wc9 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TERL_BPSPP TERL_BPSPP]] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity).
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[https://www.uniprot.org/uniprot/TERL_BPSPP TERL_BPSPP] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wc9_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wc9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 2wc9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2wc9" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Terminase 3D Structures|Terminase 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpspp]]
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[[Category: Bacillus phage SPP1]]
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[[Category: Alonso, J C]]
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[[Category: Large Structures]]
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[[Category: Antson, A A]]
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[[Category: Alonso JC]]
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[[Category: Chechik, M]]
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[[Category: Antson AA]]
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[[Category: Foster, A W]]
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[[Category: Chechik M]]
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[[Category: Kovalevskiy, O V]]
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[[Category: Foster AW]]
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[[Category: Shevtsov, M B]]
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[[Category: Kovalevskiy OV]]
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[[Category: Smits, C]]
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[[Category: Shevtsov MB]]
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[[Category: Dna translocation]]
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[[Category: Smits C]]
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[[Category: Viral protein]]
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Current revision

Crystal structure of the g2p (large terminase) nuclease domain from the bacteriophage SPP1 with bound Mn

PDB ID 2wc9

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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