3qwm
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a== | ==Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a== | ||
| - | <StructureSection load='3qwm' size='340' side='right' caption='[[3qwm]], [[Resolution|resolution]] 2.39Å' scene=''> | + | <StructureSection load='3qwm' size='340' side='right'caption='[[3qwm]], [[Resolution|resolution]] 2.39Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qwm]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3qwm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWM FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwm OCA], [https://pdbe.org/3qwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwm RCSB], [https://www.ebi.ac.uk/pdbsum/3qwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwm ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/IQEC1_HUMAN IQEC1_HUMAN] In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.<ref>PMID:11226253</ref> <ref>PMID:16461286</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Allerston C]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Chaikuad A]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Feller | + | [[Category: Feller S]] |
| - | [[Category: Felletar | + | [[Category: Felletar I]] |
| - | [[Category: Filippakopoulos | + | [[Category: Filippakopoulos P]] |
| - | [[Category: Janning | + | [[Category: Janning M]] |
| - | [[Category: Knapp | + | [[Category: Knapp S]] |
| - | [[Category: Krojer | + | [[Category: Krojer T]] |
| - | [[Category: Picaud | + | [[Category: Picaud S]] |
| - | + | [[Category: Sabe H]] | |
| - | [[Category: Sabe | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of GEP100, the plextrin homology domain of IQ motif and SEC7 domain-containing protein 1 isoform a
| |||||||||||
Categories: Homo sapiens | Large Structures | Allerston C | Arrowsmith CH | Bountra C | Chaikuad A | Edwards A | Feller S | Felletar I | Filippakopoulos P | Janning M | Knapp S | Krojer T | Picaud S | Sabe H | Weigelt J | Von Delft F
