4jhs

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==Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1==
==Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1==
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<StructureSection load='4jhs' size='340' side='right' caption='[[4jhs]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='4jhs' size='340' side='right'caption='[[4jhs]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4jhs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JHS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JHS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4jhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JHS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APOH, B2G1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jhs OCA], [http://pdbe.org/4jhs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jhs RCSB], [http://www.ebi.ac.uk/pdbsum/4jhs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jhs ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jhs OCA], [https://pdbe.org/4jhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jhs RCSB], [https://www.ebi.ac.uk/pdbsum/4jhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jhs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/APOH_HUMAN APOH_HUMAN]] Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
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[https://www.uniprot.org/uniprot/APOH_HUMAN APOH_HUMAN] Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Almo, S C]]
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[[Category: Large Structures]]
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[[Category: Bonanno, J B]]
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[[Category: Almo SC]]
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[[Category: Celikgil, A]]
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[[Category: Bonanno JB]]
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[[Category: Chan, M K]]
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[[Category: Celikgil A]]
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[[Category: Garforth, S]]
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[[Category: Chan MK]]
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[[Category: Garrett-Thomson, S C]]
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[[Category: Garforth S]]
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[[Category: Gizzi, A]]
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[[Category: Garrett-Thomson SC]]
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[[Category: Hillerich, B]]
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[[Category: Gizzi A]]
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[[Category: IFN, Atoms-to-Animals:.The Immune Function Network]]
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[[Category: Hillerich B]]
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[[Category: Lim, S]]
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[[Category: Lim S]]
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[[Category: Matikainen, B]]
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[[Category: Matikainen B]]
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[[Category: Structural genomic]]
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[[Category: Patel H]]
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[[Category: Patel, H]]
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[[Category: Rand JH]]
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[[Category: Rand, J H]]
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[[Category: Seidel R]]
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[[Category: Seidel, R]]
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[[Category: Toro R]]
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[[Category: Toro, R]]
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[[Category: Atoms-to-animals: the immune function network]]
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[[Category: Glycoprotein]]
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[[Category: Ifn]]
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[[Category: Nysgrc]]
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[[Category: Psi-biology]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1

PDB ID 4jhs

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