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3c2g

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==Crystal complex of SYS-1/POP-1 at 2.5A resolution==
==Crystal complex of SYS-1/POP-1 at 2.5A resolution==
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<StructureSection load='3c2g' size='340' side='right' caption='[[3c2g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='3c2g' size='340' side='right'caption='[[3c2g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3c2g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C2G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C2G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3c2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C2G FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3c2h|3c2h]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SYS-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans]), POP-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c2g OCA], [https://pdbe.org/3c2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c2g RCSB], [https://www.ebi.ac.uk/pdbsum/3c2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c2g ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c2g OCA], [http://pdbe.org/3c2g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3c2g RCSB], [http://www.ebi.ac.uk/pdbsum/3c2g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3c2g ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/POP1_CAEEL POP1_CAEEL]] Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase.<ref>PMID:11742996</ref> <ref>PMID:11807036</ref>
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[https://www.uniprot.org/uniprot/Q9XVI2_CAEEL Q9XVI2_CAEEL]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
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[[Category: Amaya, M F]]
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[[Category: Large Structures]]
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[[Category: Kimble, J]]
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[[Category: Amaya MF]]
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[[Category: Liu, J]]
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[[Category: Kimble J]]
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[[Category: Phillips, B T]]
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[[Category: Liu J]]
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[[Category: Xu, W]]
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[[Category: Phillips BT]]
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[[Category: Beta-catenin]]
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[[Category: Xu W]]
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[[Category: Caenorhabditis elegan]]
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[[Category: Cell adhesion-transcription complex]]
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[[Category: Developmental protein]]
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[[Category: Dna-binding]]
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[[Category: Nucleus]]
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[[Category: Phylogeny]]
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[[Category: Pop-1]]
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[[Category: Sys-1]]
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Current revision

Crystal complex of SYS-1/POP-1 at 2.5A resolution

PDB ID 3c2g

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