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4hcc

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==The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex==
==The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex==
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<StructureSection load='4hcc' size='340' side='right' caption='[[4hcc]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
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<StructureSection load='4hcc' size='340' side='right'caption='[[4hcc]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hcc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_dh5[alpha] Escherichia coli dh5[alpha]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HCC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hcc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH5alpha Escherichia coli DH5alpha]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HCC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.96&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hcb|4hcb]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2011, cpeA, JW1993, sbcB, xonA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=668369 Escherichia coli DH5[alpha]])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hcc OCA], [https://pdbe.org/4hcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hcc RCSB], [https://www.ebi.ac.uk/pdbsum/4hcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hcc ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exodeoxyribonuclease_I Exodeoxyribonuclease I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.11.1 3.1.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hcc OCA], [http://pdbe.org/4hcc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hcc RCSB], [http://www.ebi.ac.uk/pdbsum/4hcc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hcc ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EX1_ECOLI EX1_ECOLI]] Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase.
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[https://www.uniprot.org/uniprot/EX1_ECOLI EX1_ECOLI] Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase.
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==See Also==
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*[[Exonuclease 3D structures|Exonuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Exodeoxyribonuclease I]]
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[[Category: Large Structures]]
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[[Category: Gong, W]]
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[[Category: Gong W]]
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[[Category: Ji, C]]
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[[Category: Ji C]]
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[[Category: Liu, M]]
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[[Category: Liu M]]
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[[Category: Lou, T]]
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[[Category: Lou T]]
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[[Category: Qiu, R]]
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[[Category: Qiu R]]
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[[Category: Wei, J]]
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[[Category: Wei J]]
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[[Category: Dnaq family]]
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[[Category: Exonuclease c-terminal family]]
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[[Category: Hydrolase-dna complex]]
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Current revision

The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex

PDB ID 4hcc

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