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3gwv
From Proteopedia
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==Leucine transporter LeuT in complex with R-fluoxetine== | ==Leucine transporter LeuT in complex with R-fluoxetine== | ||
| - | <StructureSection load='3gwv' size='340' side='right' caption='[[3gwv]], [[Resolution|resolution]] 2.35Å' scene=''> | + | <StructureSection load='3gwv' size='340' side='right'caption='[[3gwv]], [[Resolution|resolution]] 2.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3gwv]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3gwv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. The August 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Serotonin Receptor'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_8 10.2210/rcsb_pdb/mom_2013_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GWV FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RFX:(3R)-N-METHYL-3-PHENYL-3-[4-(TRIFLUOROMETHYL)PHENOXY]PROPAN-1-AMINE'>RFX</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RFX:(3R)-N-METHYL-3-PHENYL-3-[4-(TRIFLUOROMETHYL)PHENOXY]PROPAN-1-AMINE'>RFX</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gwv OCA], [https://pdbe.org/3gwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gwv RCSB], [https://www.ebi.ac.uk/pdbsum/3gwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gwv ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/O67854_AQUAE O67854_AQUAE] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gw/3gwv_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gw/3gwv_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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*[[Leucine transporter|Leucine transporter]] | *[[Leucine transporter|Leucine transporter]] | ||
*[[Serotonin Transporter|Serotonin Transporter]] | *[[Serotonin Transporter|Serotonin Transporter]] | ||
| + | *[[Symporter 3D structures|Symporter 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Aquifex aeolicus VF5]] |
| + | [[Category: Large Structures]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Serotonin Receptor]] | [[Category: Serotonin Receptor]] | ||
| - | [[Category: Karpowich | + | [[Category: Karpowich NK]] |
| - | [[Category: Law | + | [[Category: Law CJ]] |
| - | [[Category: Reith | + | [[Category: Reith MEA]] |
| - | [[Category: Wang | + | [[Category: Wang DN]] |
| - | [[Category: Zhen | + | [[Category: Zhen J]] |
| - | [[Category: Zhou | + | [[Category: Zhou Z]] |
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Current revision
Leucine transporter LeuT in complex with R-fluoxetine
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