3ryo

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==Crystal Structure of Enhanced Intracellular Survival (Eis) Protein from Mycobacterium tuberculosis with Acetyl CoA==
==Crystal Structure of Enhanced Intracellular Survival (Eis) Protein from Mycobacterium tuberculosis with Acetyl CoA==
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<StructureSection load='3ryo' size='340' side='right' caption='[[3ryo]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='3ryo' size='340' side='right'caption='[[3ryo]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ryo]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RYO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RYO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ryo]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RYO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sxn|3sxn]], [[3uy5|3uy5]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ryo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ryo OCA], [https://pdbe.org/3ryo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ryo RCSB], [https://www.ebi.ac.uk/pdbsum/3ryo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ryo ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eis, Rv2416c, MT2489, MTCY253.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ryo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ryo OCA], [http://pdbe.org/3ryo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ryo RCSB], [http://www.ebi.ac.uk/pdbsum/3ryo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ryo ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU]] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>
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[https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: An, D R]]
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[[Category: Large Structures]]
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[[Category: Im, H N]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Kim, D J]]
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[[Category: An DR]]
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[[Category: Kim, H J]]
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[[Category: Im HN]]
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[[Category: Kim, H S]]
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[[Category: Kim DJ]]
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[[Category: Kim, J]]
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[[Category: Kim HJ]]
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[[Category: Kim, K H]]
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[[Category: Kim HS]]
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[[Category: Lee, J Y]]
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[[Category: Kim J]]
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[[Category: Lee, S J]]
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[[Category: Kim KH]]
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[[Category: Song, J]]
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[[Category: Lee JY]]
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[[Category: Suh, S W]]
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[[Category: Lee SJ]]
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[[Category: Yoon, H J]]
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[[Category: Song J]]
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[[Category: Yoon, J Y]]
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[[Category: Suh SW]]
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[[Category: Acetyltransferase]]
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[[Category: Yoon HJ]]
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[[Category: Gnat]]
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[[Category: Yoon JY]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of Enhanced Intracellular Survival (Eis) Protein from Mycobacterium tuberculosis with Acetyl CoA

PDB ID 3ryo

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