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3iez
From Proteopedia
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==Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2== | ==Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2== | ||
| - | <StructureSection load='3iez' size='340' side='right' caption='[[3iez]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='3iez' size='340' side='right'caption='[[3iez]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3iez]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3iez]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IEZ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iez OCA], [https://pdbe.org/3iez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iez RCSB], [https://www.ebi.ac.uk/pdbsum/3iez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iez ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/IQGA2_HUMAN IQGA2_HUMAN] Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3iez_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3iez_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bochkarev | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bochkarev A]] |
| - | [[Category: Crombet | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Crombet L]] |
| - | [[Category: Nedyalkova | + | [[Category: Edwards AM]] |
| - | [[Category: Park | + | [[Category: Nedyalkova L]] |
| - | + | [[Category: Park H]] | |
| - | [[Category: Tempel | + | [[Category: Tempel W]] |
| - | [[Category: Tong | + | [[Category: Tong Y]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Zhong | + | [[Category: Zhong N]] |
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Current revision
Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Bountra C | Crombet L | Edwards AM | Nedyalkova L | Park H | Tempel W | Tong Y | Weigelt J | Zhong N
