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4hx9

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==Designed Phosphodeoxyribosyltransferase==
==Designed Phosphodeoxyribosyltransferase==
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<StructureSection load='4hx9' size='340' side='right' caption='[[4hx9]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
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<StructureSection load='4hx9' size='340' side='right'caption='[[4hx9]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hx9]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_leichmanni_i"_(sic)_henneberg_1903 "bacillus leichmanni i" (sic) henneberg 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HX9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HX9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hx9]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactobacillus_leichmannii Lactobacillus leichmannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HX9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.68&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ntd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28039 "Bacillus Leichmanni I" (sic) Henneberg 1903])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside_deoxyribosyltransferase Nucleoside deoxyribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.6 2.4.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hx9 OCA], [https://pdbe.org/4hx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hx9 RCSB], [https://www.ebi.ac.uk/pdbsum/4hx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hx9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hx9 OCA], [http://pdbe.org/4hx9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hx9 RCSB], [http://www.ebi.ac.uk/pdbsum/4hx9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hx9 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NTD_LACLE NTD_LACLE]] Catalyzes the cleavage of the glycosidic bond of 2'-deoxyribonucleosides and the transfer of the deoxyribosyl moiety to an acceptor purine or pyrimidine base.<ref>PMID:7797550</ref> <ref>PMID:8805514</ref>
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[https://www.uniprot.org/uniprot/NTD_LACLE NTD_LACLE] Catalyzes the cleavage of the glycosidic bond of 2'-deoxyribonucleosides and the transfer of the deoxyribosyl moiety to an acceptor purine or pyrimidine base.<ref>PMID:7797550</ref> <ref>PMID:8805514</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Nucleoside deoxyribosyltransferase]]
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[[Category: Lactobacillus leichmannii]]
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[[Category: Kaminski, P A]]
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[[Category: Large Structures]]
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[[Category: Labesse, G]]
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[[Category: Kaminski PA]]
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[[Category: Non natural and design enzyme]]
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[[Category: Labesse G]]
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[[Category: Phosphodeoxyribosyltransferase]]
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[[Category: Rossmann fold]]
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[[Category: Transferase]]
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Current revision

Designed Phosphodeoxyribosyltransferase

PDB ID 4hx9

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