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3pnv

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==V369M mutant of Glutamyl-tRNA synthetase from Mycobacterium tuberculosis==
==V369M mutant of Glutamyl-tRNA synthetase from Mycobacterium tuberculosis==
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<StructureSection load='3pnv' size='340' side='right' caption='[[3pnv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='3pnv' size='340' side='right'caption='[[3pnv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pnv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PNV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PNV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pnv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PNV FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ja2|2ja2]], [[3pny|3pny]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gltS, gltX, MT3070, MTV012.06c, Rv2992c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pnv OCA], [https://pdbe.org/3pnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pnv RCSB], [https://www.ebi.ac.uk/pdbsum/3pnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pnv ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate--tRNA_ligase Glutamate--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.17 6.1.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pnv OCA], [http://pdbe.org/3pnv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pnv RCSB], [http://www.ebi.ac.uk/pdbsum/3pnv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pnv ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SYE_MYCTU SYE_MYCTU]] Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity).
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[https://www.uniprot.org/uniprot/SYE_MYCTU SYE_MYCTU] Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity).
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glutamate--tRNA ligase]]
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[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Bartunik, H D]]
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[[Category: Bartunik HD]]
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[[Category: Kachalova, G S]]
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[[Category: Kachalova GS]]
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[[Category: Laurinavichiute, D]]
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[[Category: Laurinavichiute D]]
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[[Category: Atp-binding]]
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[[Category: Ligase]]
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[[Category: Non-discriminating glutamyl-trna aminoacylation]]
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[[Category: Nucleotide-binding]]
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Current revision

V369M mutant of Glutamyl-tRNA synthetase from Mycobacterium tuberculosis

PDB ID 3pnv

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