3qnj
From Proteopedia
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==Crystal structure of the substrate binding domain of E.coli DnaK in complex with the antimicrobial peptide oncocin== | ==Crystal structure of the substrate binding domain of E.coli DnaK in complex with the antimicrobial peptide oncocin== | ||
| - | <StructureSection load='3qnj' size='340' side='right' caption='[[3qnj]], [[Resolution|resolution]] 2.28Å' scene=''> | + | <StructureSection load='3qnj' size='340' side='right'caption='[[3qnj]], [[Resolution|resolution]] 2.28Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3qnj]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3qnj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Oncopeltus_fasciatus Oncopeltus fasciatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QNJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QNJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qnj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qnj OCA], [https://pdbe.org/3qnj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qnj RCSB], [https://www.ebi.ac.uk/pdbsum/3qnj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qnj ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] |
==See Also== | ==See Also== | ||
| - | *[[Heat Shock | + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Oncopeltus fasciatus]] |
| - | [[Category: | + | [[Category: Straeter N]] |
| - | [[Category: | + | [[Category: Zahn M]] |
Current revision
Crystal structure of the substrate binding domain of E.coli DnaK in complex with the antimicrobial peptide oncocin
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