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3kuz
From Proteopedia
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==Crystal structure of the ubiquitin like domain of PLXNC1== | ==Crystal structure of the ubiquitin like domain of PLXNC1== | ||
| - | <StructureSection load='3kuz' size='340' side='right' caption='[[3kuz]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='3kuz' size='340' side='right'caption='[[3kuz]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3kuz]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3kuz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KUZ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kuz OCA], [https://pdbe.org/3kuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kuz RCSB], [https://www.ebi.ac.uk/pdbsum/3kuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kuz ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PLXC1_HUMAN PLXC1_HUMAN] Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity).<ref>PMID:20727575</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/3kuz_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ku/3kuz_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
| - | *[[Plexin|Plexin]] | + | *[[Plexin 3D structures|Plexin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bochkarev | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bochkarev A]] |
| - | [[Category: Buck | + | [[Category: Bountra C]] |
| - | [[Category: Crombet | + | [[Category: Buck M]] |
| - | [[Category: Edwards | + | [[Category: Crombet L]] |
| - | [[Category: Guan | + | [[Category: Edwards AM]] |
| - | [[Category: Li | + | [[Category: Guan X]] |
| - | [[Category: MacKenzie | + | [[Category: Li B]] |
| - | [[Category: Park | + | [[Category: MacKenzie F]] |
| - | + | [[Category: Park H]] | |
| - | [[Category: Tempel | + | [[Category: Tempel W]] |
| - | [[Category: Tong | + | [[Category: Tong Y]] |
| - | [[Category: Wang | + | [[Category: Wang H]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Zhong | + | [[Category: Zhong N]] |
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Current revision
Crystal structure of the ubiquitin like domain of PLXNC1
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Bountra C | Buck M | Crombet L | Edwards AM | Guan X | Li B | MacKenzie F | Park H | Tempel W | Tong Y | Wang H | Weigelt J | Zhong N
