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4lg9
From Proteopedia
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==Crystal structure of TBL1XR1 WD40 repeats== | ==Crystal structure of TBL1XR1 WD40 repeats== | ||
| - | <StructureSection load='4lg9' size='340' side='right' caption='[[4lg9]], [[Resolution|resolution]] 2.28Å' scene=''> | + | <StructureSection load='4lg9' size='340' side='right'caption='[[4lg9]], [[Resolution|resolution]] 2.28Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4lg9]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4lg9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LG9 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lg9 OCA], [https://pdbe.org/4lg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lg9 RCSB], [https://www.ebi.ac.uk/pdbsum/4lg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lg9 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TBL1R_HUMAN TBL1R_HUMAN] F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.<ref>PMID:14980219</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Edwards | + | [[Category: Bountra C]] |
| - | [[Category: He | + | [[Category: Edwards AM]] |
| - | [[Category: Min | + | [[Category: He H]] |
| - | [[Category: | + | [[Category: Min J]] |
| - | [[Category: Tempel | + | [[Category: Seitova A]] |
| - | [[Category: Wu | + | [[Category: Tempel W]] |
| - | [[Category: Xu | + | [[Category: Wu X]] |
| - | + | [[Category: Xu C]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of TBL1XR1 WD40 repeats
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Edwards AM | He H | Min J | Seitova A | Tempel W | Wu X | Xu C
