4gf9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (02:56, 21 November 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
==Structural insights into the dual strategy of recognition of peptidoglycan recognition protein, PGRP-S: ternary complex of PGRP-S with LPS and fatty acid==
==Structural insights into the dual strategy of recognition of peptidoglycan recognition protein, PGRP-S: ternary complex of PGRP-S with LPS and fatty acid==
-
<StructureSection load='4gf9' size='340' side='right' caption='[[4gf9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+
<StructureSection load='4gf9' size='340' side='right'caption='[[4gf9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4gf9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GF9 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4gf9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GF9 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LP5:(R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL)+3-HYDROXYTETRADECANOATE'>LP5</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gf9 OCA], [http://pdbe.org/4gf9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gf9 RCSB], [http://www.ebi.ac.uk/pdbsum/4gf9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gf9 ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LP5:(R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL)+3-HYDROXYTETRADECANOATE'>LP5</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gf9 OCA], [https://pdbe.org/4gf9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gf9 RCSB], [https://www.ebi.ac.uk/pdbsum/4gf9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gf9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
+
[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 24:
</StructureSection>
</StructureSection>
[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
-
[[Category: Dube, D]]
+
[[Category: Large Structures]]
-
[[Category: Kaur, P]]
+
[[Category: Dube D]]
-
[[Category: Sharma, P]]
+
[[Category: Kaur P]]
-
[[Category: Sharma, S]]
+
[[Category: Sharma P]]
-
[[Category: Singh, T P]]
+
[[Category: Sharma S]]
-
[[Category: Sinha, M]]
+
[[Category: Singh TP]]
-
[[Category: Yadav, S]]
+
[[Category: Sinha M]]
-
[[Category: Antibiotic]]
+
[[Category: Yadav S]]
-
[[Category: Antimicrobial]]
+
-
[[Category: Antimicrobial protein]]
+
-
[[Category: Immune response]]
+
-
[[Category: Peptidoglycan binding]]
+
-
[[Category: Pgrp]]
+
-
[[Category: Secreted]]
+

Current revision

Structural insights into the dual strategy of recognition of peptidoglycan recognition protein, PGRP-S: ternary complex of PGRP-S with LPS and fatty acid

PDB ID 4gf9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4gf9"
Personal tools