3f6c

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==CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF POSITIVE TRANSCRIPTION REGULATOR evgA FROM ESCHERICHIA COLI==
==CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF POSITIVE TRANSCRIPTION REGULATOR evgA FROM ESCHERICHIA COLI==
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<StructureSection load='3f6c' size='340' side='right' caption='[[3f6c]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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<StructureSection load='3f6c' size='340' side='right'caption='[[3f6c]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3f6c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F6C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3f6c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F6C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">evgA, b2369, JW2366 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f6c OCA], [http://pdbe.org/3f6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3f6c RCSB], [http://www.ebi.ac.uk/pdbsum/3f6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3f6c ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3f6c TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f6c OCA], [https://pdbe.org/3f6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f6c RCSB], [https://www.ebi.ac.uk/pdbsum/3f6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f6c ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3f6c TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EVGA_ECOLI EVGA_ECOLI]] Member of the two-component regulatory system EvgS/EvgA. Regulates the expression of emrKY operon and yfdX. Seems also to control expression of at least one other multidrug efflux operon.
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[https://www.uniprot.org/uniprot/EVGA_ECOLI EVGA_ECOLI] Member of the two-component regulatory system EvgS/EvgA. Regulates the expression of emrKY operon and yfdX. Seems also to control expression of at least one other multidrug efflux operon.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/3f6c_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/3f6c_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Almo, S C]]
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[[Category: Large Structures]]
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[[Category: Bain, K]]
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[[Category: Almo SC]]
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[[Category: Burley, S K]]
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[[Category: Bain K]]
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[[Category: Freeman, J]]
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[[Category: Burley SK]]
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[[Category: Structural genomic]]
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[[Category: Freeman J]]
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[[Category: Patskovsky, Y]]
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[[Category: Patskovsky Y]]
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[[Category: Romero, R]]
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[[Category: Romero R]]
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[[Category: Sauder, J M]]
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[[Category: Sauder JM]]
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[[Category: Smith, D]]
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[[Category: Smith D]]
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[[Category: Wasserman, S]]
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[[Category: Wasserman S]]
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[[Category: Wu, B]]
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[[Category: Wu B]]
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[[Category: Activator]]
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[[Category: Dna binding protein]]
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[[Category: Dna-binding]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: Phosphoprotein]]
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[[Category: Positive transcription regulator evga]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Two-component regulatory system]]
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Current revision

CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF POSITIVE TRANSCRIPTION REGULATOR evgA FROM ESCHERICHIA COLI

PDB ID 3f6c

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