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3k6b

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==X-ray crystal structure of the E2 domain of APL-1 from C. elegans, in complex with sucrose octasulfate (SOS)==
==X-ray crystal structure of the E2 domain of APL-1 from C. elegans, in complex with sucrose octasulfate (SOS)==
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<StructureSection load='3k6b' size='340' side='right' caption='[[3k6b]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='3k6b' size='340' side='right'caption='[[3k6b]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3k6b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K6B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3k6b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K6B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT2:2,3,4,6-TETRA-O-SULFOHEXOPYRANOSE'>NT2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rw6|1rw6]], [[3k66|3k66]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GU4:2,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">apl-1, C42D8.8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k6b OCA], [https://pdbe.org/3k6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k6b RCSB], [https://www.ebi.ac.uk/pdbsum/3k6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k6b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k6b OCA], [http://pdbe.org/3k6b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k6b RCSB], [http://www.ebi.ac.uk/pdbsum/3k6b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k6b ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A4_CAEEL A4_CAEEL]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/3k6b_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/3k6b_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Caeel]]
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[[Category: Caenorhabditis elegans]]
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[[Category: Ha, Y]]
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[[Category: Large Structures]]
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[[Category: Hoopes, J T]]
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[[Category: Ha Y]]
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[[Category: Amyloid]]
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[[Category: Hoopes JT]]
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[[Category: Amyloid precursor protein]]
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[[Category: Cell adhesion]]
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[[Category: Developmental protein]]
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[[Category: Differentiation]]
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[[Category: Glycoprotein]]
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[[Category: Heparin binding]]
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[[Category: Membrane]]
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[[Category: Neurogenesis]]
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[[Category: Transmembrane]]
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[[Category: X-ray crystal structure]]
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Current revision

X-ray crystal structure of the E2 domain of APL-1 from C. elegans, in complex with sucrose octasulfate (SOS)

PDB ID 3k6b

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