This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2ylw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:55, 20 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
==SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: ARG337LYS MUTANT IN COMPLEX WITH MES==
+
==SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: Arg337Lys MUTANT IN COMPLEX WITH MES==
-
<StructureSection load='2ylw' size='340' side='right' caption='[[2ylw]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+
<StructureSection load='2ylw' size='340' side='right'caption='[[2ylw]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2ylw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"thermonospora_fusca"_henssen_1957 "thermonospora fusca" henssen 1957]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YLW FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2ylw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YLW FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w4x|1w4x]], [[2ylx|2ylx]], [[2ylz|2ylz]], [[2ylt|2ylt]], [[2ym1|2ym1]], [[2ym2|2ym2]], [[2yls|2yls]], [[2ylr|2ylr]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylacetone_monooxygenase Phenylacetone monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.92 1.14.13.92] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ylw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ylw OCA], [https://pdbe.org/2ylw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ylw RCSB], [https://www.ebi.ac.uk/pdbsum/2ylw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ylw ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ylw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ylw OCA], [http://pdbe.org/2ylw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ylw RCSB], [http://www.ebi.ac.uk/pdbsum/2ylw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ylw ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PAMO_THEFY PAMO_THEFY]] Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl acetate. Can also oxidize other aromatic ketones (benzylacetone, alpha-methylphenylacetone and 4-hydroxyacetophenone), some aliphatic ketones (dodecan-2-one and bicyclohept-2-en-6-one) and sulfides (e.g. methyl 4-tolylsulfide).
+
[https://www.uniprot.org/uniprot/PAMO_THEFY PAMO_THEFY] Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl acetate. Can also oxidize other aromatic ketones (benzylacetone, alpha-methylphenylacetone and 4-hydroxyacetophenone), some aliphatic ketones (dodecan-2-one and bicyclohept-2-en-6-one) and sulfides (e.g. methyl 4-tolylsulfide).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 2ylw" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2ylw" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Thermonospora fusca henssen 1957]]
+
[[Category: Large Structures]]
-
[[Category: Phenylacetone monooxygenase]]
+
[[Category: Thermobifida fusca]]
-
[[Category: Dudek, H M]]
+
[[Category: Dudek HM]]
-
[[Category: Fraaije, M W]]
+
[[Category: Fraaije MW]]
-
[[Category: Martinoli, C]]
+
[[Category: Martinoli C]]
-
[[Category: Mattevi, A]]
+
[[Category: Mattevi A]]
-
[[Category: Orru, R]]
+
[[Category: Orru R]]
-
[[Category: Pazmino, D E.Torres]]
+
[[Category: Royant A]]
-
[[Category: Royant, A]]
+
[[Category: Torres Pazmino DE]]
-
[[Category: Weik, M]]
+
[[Category: Weik M]]
-
[[Category: Baeyer-villiger reaction]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Oxygenase]]
+

Current revision

SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: Arg337Lys MUTANT IN COMPLEX WITH MES

PDB ID 2ylw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ylw"
Personal tools