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5efj

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==Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HC toxin==
==Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HC toxin==
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<StructureSection load='5efj' size='340' side='right' caption='[[5efj]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
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<StructureSection load='5efj' size='340' side='right'caption='[[5efj]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5efj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Bipolaris_zeicola Bipolaris zeicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EFJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5efj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bipolaris_zeicola Bipolaris zeicola] and [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EFJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5OM:(2S)-2-AMINO-8,8-DIHYDROXY-8-[(2S)-OXIRAN-2-YL]OCTANOIC+ACID'>5OM</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5OM:(2S)-2-AMINO-8,8-DIHYDROXY-8-[(2S)-OXIRAN-2-YL]OCTANOIC+ACID'>5OM</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5edu|5edu]], [[5eef|5eef]], [[5eei|5eei]], [[5eek|5eek]], [[5eem|5eem]], [[5een|5een]], [[5ef7|5ef7]], [[5ef8|5ef8]], [[5efb|5efb]], [[5efg|5efg]], [[5efh|5efh]], [[5efk|5efk]], [[5efn|5efn]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5efj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5efj OCA], [https://pdbe.org/5efj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5efj RCSB], [https://www.ebi.ac.uk/pdbsum/5efj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5efj ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5efj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5efj OCA], [http://pdbe.org/5efj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5efj RCSB], [http://www.ebi.ac.uk/pdbsum/5efj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5efj ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/F8W4B7_DANRE F8W4B7_DANRE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5efj" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5efj" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bipolaris zeicola]]
[[Category: Bipolaris zeicola]]
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[[Category: Histone deacetylase]]
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[[Category: Danio rerio]]
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[[Category: Christianson, D W]]
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[[Category: Large Structures]]
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[[Category: Hai, Y]]
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[[Category: Christianson DW]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Hai Y]]

Current revision

Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HC toxin

PDB ID 5efj

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