This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5kdr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:58, 27 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==The crystal structure of carboxyltransferase from Staphylococcus Aureus bound to the antimicrobial agent moiramide B.==
==The crystal structure of carboxyltransferase from Staphylococcus Aureus bound to the antimicrobial agent moiramide B.==
-
<StructureSection load='5kdr' size='340' side='right' caption='[[5kdr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+
<StructureSection load='5kdr' size='340' side='right'caption='[[5kdr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5kdr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KDR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KDR FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5kdr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_RF122 Staphylococcus aureus RF122] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_USA300 Staphylococcus aureus subsp. aureus USA300]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KDR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KDR FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YT5:MOIRAMIDE+B'>YT5</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2f9i|2f9i]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YT5:MOIRAMIDE+B'>YT5</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_carboxylase Acetyl-CoA carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.4.1.2 6.4.1.2] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kdr OCA], [https://pdbe.org/5kdr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kdr RCSB], [https://www.ebi.ac.uk/pdbsum/5kdr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kdr ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kdr OCA], [http://pdbe.org/5kdr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kdr RCSB], [http://www.ebi.ac.uk/pdbsum/5kdr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kdr ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ACCA_STAA3 ACCA_STAA3]] Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.[HAMAP-Rule:MF_00823] [[http://www.uniprot.org/uniprot/ACCD_STAAB ACCD_STAAB]] Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
+
[https://www.uniprot.org/uniprot/ACCA_STAA8 ACCA_STAA8] Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.[HAMAP-Rule:MF_00823]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 5kdr" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5kdr" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Acetyl-CoA carboxylase]]
+
[[Category: Large Structures]]
-
[[Category: Anzalone, N]]
+
[[Category: Staphylococcus aureus RF122]]
-
[[Category: Neau, D]]
+
[[Category: Staphylococcus aureus subsp. aureus USA300]]
-
[[Category: Pakhomova, S]]
+
[[Category: Anzalone N]]
-
[[Category: Silvers, M A]]
+
[[Category: Neau D]]
-
[[Category: Silvers, W C]]
+
[[Category: Pakhomova S]]
-
[[Category: Taylor, C M]]
+
[[Category: Silvers MA]]
-
[[Category: Waldrop, G L]]
+
[[Category: Silvers WC]]
-
[[Category: Acetyl-coa carboxylase]]
+
[[Category: Taylor CM]]
-
[[Category: Antibiotic]]
+
[[Category: Waldrop GL]]
-
[[Category: Carboxyltransferase]]
+
-
[[Category: Enolate]]
+
-
[[Category: Moiramide b]]
+
-
[[Category: Transferase]]
+

Current revision

The crystal structure of carboxyltransferase from Staphylococcus Aureus bound to the antimicrobial agent moiramide B.

PDB ID 5kdr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5kdr"
Personal tools