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4pu2

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==Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine L-(R)-LeuP==
==Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine L-(R)-LeuP==
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<StructureSection load='4pu2' size='340' side='right' caption='[[4pu2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4pu2' size='340' side='right'caption='[[4pu2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pu2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PU2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PU2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pu2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_MC58 Neisseria meningitidis MC58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PU2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PU2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLU:LEUCINE+PHOSPHONIC+ACID'>PLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.095&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PLU:LEUCINE+PHOSPHONIC+ACID'>PLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gtq|2gtq]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pu2 OCA], [https://pdbe.org/4pu2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pu2 RCSB], [https://www.ebi.ac.uk/pdbsum/4pu2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pu2 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pu2 OCA], [http://pdbe.org/4pu2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pu2 RCSB], [http://www.ebi.ac.uk/pdbsum/4pu2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pu2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9JYV4_NEIMB Q9JYV4_NEIMB]
==See Also==
==See Also==
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*[[Aminopeptidase|Aminopeptidase]]
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Membrane alanyl aminopeptidase]]
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[[Category: Large Structures]]
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[[Category: Berlicki, L]]
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[[Category: Neisseria meningitidis MC58]]
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[[Category: Joachimak, A]]
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[[Category: Berlicki L]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak A]]
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[[Category: Mucha, A]]
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[[Category: Mucha A]]
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[[Category: Mulligan, R]]
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[[Category: Mulligan R]]
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[[Category: Nocek, B]]
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[[Category: Nocek B]]
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[[Category: Vassiliou, S]]
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[[Category: Vassiliou S]]
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[[Category: Aminopeptidase]]
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[[Category: Aminopeptidase n]]
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[[Category: Apn]]
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[[Category: Hydrolase]]
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[[Category: Mcsg]]
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[[Category: Psi-biology]]
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Current revision

Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine L-(R)-LeuP

PDB ID 4pu2

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