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4a4f
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==Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine== | ==Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine== | ||
| - | <StructureSection load='4a4f' size='340' side='right' caption='[[4a4f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='4a4f' size='340' side='right'caption='[[4a4f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4a4f]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4a4f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A4F FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a4e|4a4e]], [[4a4g|4a4g]], [[4a4h|4a4h]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4a4e|4a4e]], [[4a4g|4a4g]], [[4a4h|4a4h]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4f OCA], [https://pdbe.org/4a4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a4f RCSB], [https://www.ebi.ac.uk/pdbsum/4a4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a4f ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SPF30_HUMAN SPF30_HUMAN]] Necessary for spliceosome assembly. Overexpression causes apoptosis.<ref>PMID:9817934</ref> <ref>PMID:11331595</ref> <ref>PMID:11331295</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Englbrecht, C]] | [[Category: Englbrecht, C]] | ||
[[Category: Fessas, D]] | [[Category: Fessas, D]] | ||
Current revision
Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine
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