3vco
From Proteopedia
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==Schistosoma mansoni Dihydrofolate reductase== | ==Schistosoma mansoni Dihydrofolate reductase== | ||
| - | <StructureSection load='3vco' size='340' side='right' caption='[[3vco]], [[Resolution|resolution]] 1.95Å' scene=''> | + | <StructureSection load='3vco' size='340' side='right'caption='[[3vco]], [[Resolution|resolution]] 1.95Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3vco]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3vco]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VCO FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.946Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vco OCA], [https://pdbe.org/3vco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vco RCSB], [https://www.ebi.ac.uk/pdbsum/3vco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vco ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DYR_SCHMA DYR_SCHMA] Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.<ref>PMID:28288799</ref> | ||
==See Also== | ==See Also== | ||
| - | *[[Dihydrofolate reductase|Dihydrofolate reductase]] | + | *[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]] |
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Schistosoma mansoni]] |
| - | [[Category: Cassago | + | [[Category: Cassago A]] |
| - | [[Category: DeMarco | + | [[Category: DeMarco R]] |
| - | [[Category: Pereira | + | [[Category: Pereira HM]] |
| - | [[Category: Romanello | + | [[Category: Romanello L]] |
| - | [[Category: Serrao | + | [[Category: Serrao VHB]] |
| - | + | ||
| - | + | ||
Current revision
Schistosoma mansoni Dihydrofolate reductase
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