4un8

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==THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2)==
==THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2)==
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<StructureSection load='4un8' size='340' side='right' caption='[[4un8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='4un8' size='340' side='right'caption='[[4un8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4un8]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UN8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UN8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4un8]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfurococcus_mucosus Desulfurococcus mucosus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UN8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4un6|4un6]], [[4un7|4un7]], [[4un9|4un9]], [[4una|4una]], [[4unb|4unb]], [[4unc|4unc]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4un8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4un8 OCA], [http://pdbe.org/4un8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4un8 RCSB], [http://www.ebi.ac.uk/pdbsum/4un8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4un8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4un8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4un8 OCA], [https://pdbe.org/4un8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4un8 RCSB], [https://www.ebi.ac.uk/pdbsum/4un8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4un8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DMO1_DESMO DMO1_DESMO]] Endonuclease involved in intron homing. Recognizes a recognizes up to 20 bp of DNA in the 23S rRNA gene intron. It has a slow turnover rate and cuts the coding strand with a slight preference over the non-coding strand.
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[https://www.uniprot.org/uniprot/DMO1_DESMO DMO1_DESMO] Endonuclease involved in intron homing. Recognizes a recognizes up to 20 bp of DNA in the 23S rRNA gene intron. It has a slow turnover rate and cuts the coding strand with a slight preference over the non-coding strand.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Endonuclease|Endonuclease]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Gomez, H]]
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[[Category: Desulfurococcus mucosus]]
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[[Category: Marcaida, M J]]
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[[Category: Large Structures]]
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[[Category: Molina, R]]
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[[Category: Synthetic construct]]
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[[Category: Montoya, G]]
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[[Category: Gomez H]]
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[[Category: Orozco, M]]
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[[Category: Marcaida MJ]]
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[[Category: Prieto, J]]
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[[Category: Molina R]]
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[[Category: Redondo, P]]
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[[Category: Montoya G]]
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[[Category: Stella, S]]
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[[Category: Orozco M]]
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[[Category: Catalysis]]
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[[Category: Prieto J]]
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[[Category: Dna-binding protein]]
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[[Category: Redondo P]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Stella S]]
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[[Category: Protein-dna interaction]]
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2)

PDB ID 4un8

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